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Higher strengths (3 mg and 4.5 mg) are available for patients requiring intensification

Glossary AGE advanced glycosylation end products AGT angiotensinogen AGTR1/2 angiotensin II receptor type 1/2 AMI acute myocardial infarction Ang II angiotensin II BP biological process CASP1 caspase 1 CC cellular component CCNA2 cyclin A2 CCND1 cyclin D1 ChIP-seq chromatin immunoprecipitation-squence CTSZ cathepsin Z CXCR4 C-X-C motif chemokine receptor 4 ECM extracellular matrix EDNRA endothelin receptor type A EPC edge percolated component F7 coagulation factor VII GLP-1 glucagon-like peptide-1 GLP-1RAs GLP-1 receptor agonists GO gene ontology ITGA9/11 integrin subunit alpha 9/11 KEGG Kyoto encyclopedia of genes and genes MAFA MAF BZIP transcription factor A MAFB MAF BZIP transcription factor B MCC maximal clique centrality MCODE molecular complex detection MF molecular function MI myocardial infarction MME membrane metalloendopeptidase MMP1/2/9 matrix metallopeptidase 1/2/9 MNC maximum neighborhood component NES normalized enrichment score NF-B nuclear factor kappa B subunit 1 NLRC4 NLR family CARD domain containing 4 OMIM online mendelian inheritance in man ox-LDL oxidized low density lipoprotein PharmGKB pharmacogenetics and pharmacogenomics knowledge base PPI protein-protein interaction RAAS renin-angiotensin-aldosterone system RAGE receptor for advanced glycosylation end products RAS renin-angiotensin system REN renin SCN5A sodium voltage-gated channel alpha subunit 5 SIRT1 sirtuin 1 SMILES simplified molecular input line entry system STAT3 signal transducer and activator of transcription 3 T2DM type 2 diabetes mellitus TFPI tissue factor pathway inhibitor TGFB1 transforming growth factor beta 1 TIMP1/2/3 tissue inhibitor of metalloproteinases 1/2/3 TSV tab separated values TTD therapeutic target database

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clinicians are referred to ADA and EASD pregnancy guidelines
