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Experts believe it could be ready in 23 years if studies continue to be successful

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These drugs are contraindicated in patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Other potential risks include: Acute pancreatitis Gallbladder disease (cholelithiasis, cholecystitis) Acute kidney injury Hypersensitivity reactions Patients should be monitored for persistent abdominal pain, changes in renal function, and other signs that may require discontinuation or additional workup

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But Wenz says researchers are still learning about less-obvious benefits of metformin

[DOI] [PMC free article] [PubMed] [Google Scholar] 232.Mulvaney C.A., Duarte G.S., Handley J., Evans D.J., Menon S., Wyse R