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Discussion Since reports to the European Medicines Agency of depression and suicidality in patients taking GLP-1RAs, large studies have demonstrated conflicting results regarding the association of these drugs with mood disturbance and suicidality

Many patients who initially experience GI symptoms improve within the first several months of therapy

Brighton CA, Rievaj J, Kuhre RE, et al

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These workouts can help preserve muscle mass and improve your metabolism

This review synthesizes current evidence on body composition changes observed during GLP-1 receptor agonist therapy, summarizes mechanistic and clinical data on the effects of testosterone and TRT on skeletal muscle and fat-free mass, and discusses the theoretical and clinical considerations relevant to lean mass preservation in this context