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Most people notice changes fairly early: Weeks 24: appetite decreases, cravings feel more manageable Months 23: consistent weight loss begins Months 612: the most significant weight loss typically occurs Results vary, but steady progress, rather than rapid drops, is usually a good sign the medication is working well

This agent has also antifibrotic effects and improves insulin sensitivity

The beta diversity of gut microbiota was significantly differed between these two groups, as well as some bacteria, such as Bacteroides dorei and Roseburia inulinivorans

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There was no significant difference in the risk of all-cause mortality (0.94

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