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Avg weight loss (72 weeks): ~15% (SURMOUNT-1) 10 mg Weeks 1316 The most common maintenance dose

These metabolic advantages may also extend to renal protection, according to a post-hoc study that included data from the two trials

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Effect of semaglutide on kidney function across different levels of baseline HbA1c, blood pressure, body weight & albuminuria in SUSTAIN 6 & PIONEER 6 doi.org/10.1093/ndt/gf A clinically meaningful reduction in risk of CKD progression was observed with semaglutide vs placebo Effect of semaglutide on kidney function across different levels of baseline HbA1c, blood pressure, body weight & albuminuria in SUSTAIN 6 & PIONEER 6 doi.org/10.1093/ndt/gf A clinically meaningful reduction in risk of CKD progression was observed with semaglutide vs placebo