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Supplementation should be based on confirmed deficiency or specific medical advice rather than routine practice

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Researchers interested in replicating or extending this work may request access to the TriNetX platform (Available online: through their affiliated institutions, subject to approval by TriNetX and compliance with their data use policies

However, due to rapid inactivation by DPP-4 (132), continuous infusion was required, making it unsuitable for regular use in a real world setting

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