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Glutamate antagonists have different effects on spontaneous locomotor activity in rats

Once in circulation, GLP-1 travels to target tissues, including the pancreas, where it enhances insulin secretion, and the brain, where it promotes satiety

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One 2026 narrative review concluded that GLP-1 receptor agonist therapy is associated with meaningful nutritional deficiencies and that individualized nutritional assessment and lab evaluation may be appropriate, especially in people at higher risk of malnutrition

Without support from calcium, magnesium, and vitamin D, bone health remains vulnerable
