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Effects of glepaglutide, a novel long-acting glucagon-like peptide-2 analogue, on markers of liver status in patients with short bowel syndrome: findings from a randomised phase 2 trial

As noted by others (Khan et al., 2020), it remains to be clarified if use of GLP-1 RAs is safe across the HF phenotypes

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Any study protocol should include regular monitoring of heart rate and other vital signs

Despite this solid experimental foundation, clinical evaluation remains limited due to variations in extraction procedures, compound complexity, dosage inconsistencies, and the lack of standardized formulations