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These medications are superior to compounded versions due to their reliable, regulatory oversight and proven effectiveness

Currently two of the drugs Zepbound for obesity and Mounjaro for Type 2 diabetes can't legally be compounded, but the FDA said it will turn a blind eye to the practice for now while it evaluates whether it was right to end the shortage earlier this fall

However, the structured dose titration protocols used in trials are absent in self-administration scenarios, significantly increasing the likelihood and severity of these reactions

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