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2 Despite the proven efficacy of metformin, blood glucose often remains uncontrolled with monotherapy

Heres what they do: Help your body release insulin when your blood sugar is high Reduce another hormone called glucagon that usually increases blood sugar Slow down digestion , so you feel full for longer Send signals to your brain to curb hunger and reduce cravings This multi-action approach is what makes GLP-1 drugs helpful in both type 2 diabetes and weight management If Our Body Already Makes GLP-1, Why Take It From Outside

Ravi Rao January 2, 2026 JAMA Surgery has published a new research which demonstrates that bariatric surgery continues to serve as an effective treatment for severe obesity as it produces better results than GLP 1 weight-loss medications

Like any medication, there are potential side effects and you have to weigh the pros and cons

Effects of Ketogenic Diet on Health Outcomes: An Umbrella Review of Meta-Analyses of Randomized Clinical Trials

has received consultancy and/or lecture fees from companies with an interest in developing and marketing incretin-based therapies for treatment of type 2 diabetes mellitus (Boehringer Ingelheim, Lilly, Merck/MSD and Novo Nordisk)