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The animals were randomly divided into four experimental groups: untreated control animals (C) received 1 mL of the formulation containing the vehicle (n = 6)
T., Gamble, J

56,57,58 It is possible that GLP-1RAs affect vascular dynamics via the autonomic nervous system and lower systemic blood pressure, which could affect optic nerve head perfusion and increase NAION risk

Excitatory neurotransmitters like glutamate facilitate synaptic transmission within the dorsal horn and dorsal root ganglia (DRG), amplifying pain transmission through ascending pathways conveying nociceptive signals from the periphery to the brain (Latremoliere and Woolf 2009

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If you do decide to switch, continue taking your current medication and dose until your prescriber instructs you to stop
