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Women may report feeling too warm at night, even before classic hot flashes appear

The survodutide versus tirzepatide comparison highlights how different receptor pairings produce different metabolic effects despite comparable weight loss magnitudes

A precision stratification approach would enroll participants according to baseline HbA1c strata, degree of insulin resistance, adiposity, systemic inflammatory burden, background medication class, and verified curcumin plasma concentration, substantially improving the interpretability and translational relevance of trial outcomes

Competing interests ML, FL, CR-D, AL, and RP are employees of, and are shareholders in, Sanofi

This is why provider-supervised weight loss programs often produce better long-term outcomes than self-directed dieting

When the drug shortage ended, the FDA banned the sale of compounded semaglutide after May 2025