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The incidence of selected gastrointestinal adverse reactions in patients treated with Januvia was as follows: abdominal pain (Januvia 100 mg, 2.3%

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A: If you have a history of varicose veins, leg swelling, DVT, or spend significant time sitting or standing at work, a vein evaluation before starting is clinically prudent

doi: 10.1002/jnr.21483 34 HamiltonAPattersonSPorterDGaultVAHolscherC

Front Endocrinol 10:389 Godinho R, Mega C, Teixeira-de-Lemos E, Carvalho E, Teixeira F, Fernandes R, Reis F (2015) The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A Me Too or the Special One Antidiabetic Class

Based on Immgen ( and previous studies (7, 11, 20), most immune cells except for gut intraepithelial T lymphocytes show only very low expression of the classical GLP-1R