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doi: 10.1056/NEJMoa1612917 81 RuffCTBaronMImKODonoghueMLFiedorekFTSabatineMS

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Most agents undergo proteolytic degradation and renal elimination

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A double-blind-randomized controlled trial

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The peptide cost calculator confirms that the cost-per-unit-of-benefit favors 8mg over 12mg for most researchers

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