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95% CI 1.6, 0.66), SGLT2is/metformin (WMD: 0.43

The bottom line GLP-1s were first FDA-approved for managing type 2 diabetes and obesity, but research is showing that they might have much wider reaching health benefits
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Additionally, several next-generation GLP-1 therapies are in late-stage development, offering new administration methods and expanded indications in 2026

Supplementary data Supplementary data are available at Human Reproduction Open online
