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Table 4 Results of a 26-week Trial of Liraglutide Injection as Add-on to Metformin in Adults with Type 2 Diabetes Mellitus a Liraglutide Injection Compared to Sitagliptin, Both as Add-on to Metformin In this 26-week, open-label trial, 665 adult patients with type 2 diabetes mellitus on a background of metformin 1,500 mg per day were randomized to liraglutide injection 1.2 mg once daily, liraglutide injection 1.8 mg once daily or sitagliptin 100 mg once daily, all dosed according to approved labeling

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How Semaglutide Affects Your Body's Weight Loss Signals Semaglutide mimics glucagon-like peptide-1 (GLP-1), a natural hormone that tells your brain when you are full

Obese patients have large fat stores, which create a greater potential for energy mobilization when appetite and calorie intake are reduced