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We used softwares including AutoDock MGL Tool 1.5.7, GROMACS 2023, PyMOL, Discovery studio, Chimera 1.17.3, VMD (Visual Molecular Dynamics), origin2024, GraphPad Prism 8.0, Adobe PhotoShop 6.0, etc., and web tools including pkCSM, SwissADME, PreADMET, ProTOX 3.0, FastDRH, etc

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