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A recent propensity-matched cohort study also identified obesity as a risk factor for corticosteroid use, therapy escalation, and colectomy in UC patients (85)

Patients with T2D not adequately controlled on therapy with metformin and insulin glargine as baseline therapy received either tirzepatide at the doses used in the SURPASS trials or placebo during the 40-week study setting

While we have not tested the full combination in females, we have tested GDF8 and ActA blockade in lean female monkeys 28 and in postmenopausal women in our Phase 1 clinical study in the accompanying manuscript (Gonzalez Trotter et al

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It was the wrong call, no two ways around it