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Hypoglycemia: Low risk due to glucose-dependent mechanism of action

In the present study using obese mice fed HFD for 5 weeks or longer, food intake in LP (7:3019:30) was approximately doubled, whereas that in dark period (DP, 19:307:30) unaltered, exhibiting LP-specific hyperphagia accompanied by daily hyperphagia (Figs

Furthermore, as HCPs lack prior experience with muscle-preserving therapies, innovators will need to provide practical education on when and how to use such therapies, likely alongside other AOMs, including diagnostic approaches to identify eligible patient segments in routine practice
In this study 35 (56%) patients exposed to GLP-1RAs had an increased incidence of RGC as compared to 12 (19%) of the non-users, a finding that persisted after adjustment for confounders
This reduction in DPP4 expression may contribute to the dysfunctional immune regulation observed in SLE

J Diabetes Sci Technol Advance Access published on Mar 11, 2024, doi: 10.1177/19322968241231565
