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Alzheimers Dement 17(1):115124 [DOI] [PMC free article] [PubMed] [Google Scholar] Aronne LJ et al (2024) Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: the SURMOUNT-4 randomized clinical trial

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When GIP receptor activation combines with GLP-1 stimulation, as it does with tirzepatide dosing protocols , the result is enhanced insulin sensitivity, improved lipid metabolism, and a reduction in pathological fat deposition