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adults eligible for this trial, mean HbA1c was projected to decline from 7.5% at baseline to 6.79% at week 104, and body weight from 85.0 kg to 80.8 kg with the use of oral semaglutide, based on treatment effects observed in the SOUL trial (Fig

Overall conclusion: This FAERS study identifies potential safety signals but does not demonstrate that semaglutide medications are a cause of hair loss in these individuals

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For GLP-1 agonists like semaglutide, this means documented medical history review, contraindication screening (personal or family history of medullary thyroid carcinoma, MEN2 syndrome, or severe gastroparesis), and baseline metabolic panel review