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In a study of older men, restless leg syndrome was associated with a higher mortality rate, even after controlling for a number of other variables.[ref] PLMD is negatively correlated with REM sleep duration and is associated with poorer cognitive function in middle-aged and elderly individuals

With the utilization of de-identified data, our study was exempt from an institutional review board

These reports included five deaths

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Whilst day-to-day hypoglycaemia was not coded in our network, we employed hypoglycaemia requiring hospital admission as a surrogate outcome of severe hypoglycaemia and there was no difference in the incidence in our cohort compared to the general population with type 1 diabetes