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Visual Field Defects Visual field defects (independent of elevated intraocular pressure) have been reported in clinical trials and in postmarketing experience in patients receiving topiramate

Refrigeration requirements Compounded tirzepatide must be refrigerated at 36 to 46 degrees Fahrenheit (2 to 8 degrees Celsius)

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Constipation becomes more common at this level, and some users report what researchers call "sulfur burps," a distinctive side effect related to slowed gastric emptying

For a medication that requires refrigeration, this raises legitimate potency questions

Without the artificial appetite suppression, hunger returns to baseline levels