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Whilst insomnia itself is not listed in the Ozempic SmPC, several common adverse reactions associated with this medication may indirectly interfere with sleep quality and duration

[DOI] [PubMed] 110
Some studies have reported GLP-1R expression in both transformed hepatocyte cell lines (HuH7 and Hep-G2) and in primary human hepatocytes
Dipeptidylpeptidase IV hydrolyses gastric inhibitory polypeptide, glucagonlike peptide1 (736) amide, peptide histidine methionine and is responsible for their degradation in human serum
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Native GLP-1 has no use therapeutically, but the advent of GLP-1R agonists that have much longer half-lives has enabled GLP-1based actions for therapeutic uses as a viable option 57 )
