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Semaglutide acts as a GLP-1 receptor agonist, binding to receptors in the hypothalamus to reduce hunger signaling while simultaneously slowing gastric emptying

Priority medicines include: GLP-1 receptor agonists such as semaglutide dual GIP/GLP-1 agonists such as tirzepatide future triple-receptor agonists SGLT2 inhibitors for heart and kidney protection medicines targeting liver fat, inflammation and insulin resistance Trials must examine long-term safety, muscle preservation, affordability and what happens after treatment stops

Prevalence and clinical outcome of hyperglycemia in the perioperative period in noncardiac surgery

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