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After a median follow-up of 2 years, the incidence of new or worsening nephropathy in the semaglutide group was lower than that in the placebo group [HR 0.64 (95% CI: 0.460.88, p=0.05)]

Reiss MJ, Han Y-P, Garcia E, Goldberg M, Yu H, Garner WL

Together, these findings illustrate the consistency of alcohol-reducing effects across real-world, biomarker-based, and neuroimaging-supported studies, despite heterogeneity in design and outcome measures

Overall, the selected trials had a low to moderate risk of bias
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about 0.7 inches in the placebo takers

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