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Combining phentermine and semaglutide requires careful medical oversight due to overlapping mechanisms and cardiovascular effects

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No, but semaglutide did improve a persistence/effort in a this secondary analysis: Although it failed to improve mood or cognition in this original study (randomized, major depression with overweight/obesity)
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Lilly is testing the drug across conditions, primarily diabetes, obesity, osteoarthritis and sleep apnea
