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These two peptides (GLP-1 and GIP) potentiate glucose-stimulated insulin secretion in an additive manner, likely contribute equally to the incretin effect and together can fully account for the majority of the incretin effect in humans

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they will likely reduce or discontinue one or more blood pressure medications to restore safe blood pressure levels while continuing semaglutide for weight loss benefits

Rather than a drug-specific anomaly, they noted that these trends point to a broader therapeutic role for incretin-based therapies in ocular health, with tirzepatide potentially amplifying this benefit

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