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In the meta-analysis, SGLT2 inhibitors significantly reduced major adverse cardiovascular events (MACE), hospitalization for heart failure (HF) plus CV death, and progression of CKD by 11%, 23% and 33%, respectively, compared to placebo

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The meta-analysis included 11 trials with 82,140 participants, providing robust evidence of the efficacy of GLP-1 RAs in reducing stroke risk