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The cardioprotective effects of GLP-1RAs include anti-inflammatory actions, reduction of myocardial ischemia injury, modifications in the synthesis and secretion of lipids, and improvement of endothelial dysfunction (109)
58 GLP-2 The primary physiological effect of GLP-2 appears to be within the intestine, where GLP-2 promotes small and large intestinal growth through stimulating cell proliferation and inhibiting apoptosis in the crypt compartment

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Retatrutide represents a newer category of metabolic therapy currently under clinical investigation

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