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Documented experimental evidence, extracted from important preclinical studies, is described accordingly in Table 2

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The role of estrogens in control of energy balance and glucose homeostasis
SMC Chair Dr Rob Peel said: "Semaglutide will provide a useful treatment option to help reduce major cardiovascular events in patients who are overweight and have cardiovascular disease." Speaking after the announcement, Sebnem Avsar Tuna, General Manager Novo Nordisk UK said: We are delighted that the SMC has recognised the value semaglutide can bring to the people in Scotland who are living with established cardiovascular disease and overweight or obesity, where the threat of a secondary event is a constant reality