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GLP-1 plays an important role in regulating appetite by creating the sensation of feeling full after a meal

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Sirtuins (SIRTs) are a group of proteins that are NAD+-dependent, and thanks to their properties, they are able to change the acetylation profile of proteins and post-translationally modify their functions, too

They are primarily used in the management of type 2 diabetes (T2D).

Glucagon-like peptides (GLP-1 and GLP-2) are two proglucagon-derived intestinal hormones that mediate distinct physiological functions through two related receptors (GLP-1R and GLP-2R) which are important drug targets for metabolic disorders and Crohns disease, respectively

We break down the key differences in mechanism, evidence base, side effects, and who each one is actually relevant for.