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Clinicians should not treat weight loss and glycemic control as separate goals

metformin, sulfonylureas, TZDs, etc.) address only one of the underlying pathophysiology - lowering postprandial glucose levels, but their safety profiles and side effects, such as weight gain and hypoglycemia, may present challenges and limitations in their clinical use

Bottom line If you are comparing Wegovy, Ozempic, Zepbound, Saxenda, Victoza, and Trulicity, the biggest takeaway is simple: the best medication depends entirely on the clinical goal

References 1.The Centers for Disease Control and Prevention

Beyond Weight Loss: The Key Benefits of Microdosing GLP-1 Improved Blood Sugar Control Stabilizes glucose levels and reduces insulin resistanceeven in non-diabetics

Thyroid function tests TSH, T3, and T4 are sometimes monitored if there are specific clinical concerns
