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Exenatide (Bydureon) had the most preapproval patents at 31, followed by insulin glargine/lixisenatide (Soliqua) at 26, and insulin degludec/liraglutide (Xultophy) at 23

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Kidney Int 97:202212 Gutzwiller J-P, Tschopp S, Bock A, Zehnder CE, Huber AR, Kreyenbuehl M et al (2004) Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men

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