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Preclinical studies have shown that GLP-1RAs play a role in the immunomodulation of atherosclerosis, affecting multiple pathways involved in plaque development and progression

Findings In this randomized clinical trial including 60 US adults with a prespecified interim analysis, the rate of clinically significant RGV was 25.0% vs 3.1% when GLP-1/GIP agonists were continued vs held, respectively, in the periprocedural period

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By 2022, that number had climbed to 42.5%about 107 million people

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