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Patients who fail to respond adequately to semaglutide often respond better to tirzepatide, not because of dose differences but because the dual mechanism addresses different pathways

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Nutritional approaches tailored to perimenopausal physiology include: Protein optimisation : Moderate protein intake (around 1.01.2 g/kg body weight daily for most women) may help preserve muscle mass and enhance satiety

Those with a BMI of 27 or higher who also have associated health conditions, such as type 2 diabetes, may also qualify

Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y