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But this lower GLP-1 potency is compensated by the additional GIP receptor activation, which produces effects that semaglutide cannot replicate

Compounded tirzepatide must use approved bulk API from compliant manufacturers
If those results hold up in the real world, that would make it the most potent of the injectable weight loss medications
[DOI] [PMC free article] [PubMed] [Google Scholar] 161

Status: Currently in phase-2 clinical trials
