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[DOI] [PubMed] [Google Scholar] 118.Zinman B, Gerich J, Buse JB, Lewin A, Schwartz S, Raskin P, Hale PM, Zdravkovic M, Blonde L LEAD-4 Study Investigators

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Burmeister MA, Ferre T, Ayala JE, King EM, Holt RM, Ayala JE

J Clin Endocrinol Metab 2023

In energy-demanding RGCs, while basal mitophagy is physiologically essential, excessive activation can lead to energy depletion and cellular demise

The question has gained visibility due to anecdotal accounts of so-called Ozempic babies. This paper aims to delineate mechanisms linking GLP-1 receptor activation with reproductive outcomes, review clinical data on fertility, and outline implications for practice