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It randomised 156 participants with early disease to daily subcutaneous lixisenatide or placebo for 12 months, followed by a 2-month washout

Inclusion criteria for the literature were [1]: trials designed as randomized, double-blind, placebo-controlled studies [2]

One such study by McClean and colleagues [61] observed that liraglutide can cross the blood-brain barrier in substantial amounts and can prevent deficits in the water maze task performance and object recognition in AD model mice

For instance, several cases of altered kidney function were reported after the administration of exenatide twice daily

Side Effects and Safety: Short-Term Considerations Most people will encounter gastrointestinal effects early in therapy, especially during dose escalation

Thats according to a small clinical trial run by Novo Nordisk, so real-life results may vary