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New data also suggest that the use of GLP-1 RAs before metabolic or bariatric surgery may help high-risk patients with extreme obesity (BMI 70 kg/m 2 ) lower the risk of post-operative complications

Interestingly, clinical data from the SURMOUNT trials showed that mood improvement was dose-dependent, meaning higher doses were associated with better mood scores overall

Lastly, and quite critically, is the issue of cost and insurance coverage
