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[6] [7] This delayed emptying creates a sensation of fullness that contributes to weight loss but can also trigger nausea, particularly when the stomach remains distended

Moreover, it can also cause hypoglycemia (low blood glucose levels)

First, failure occurring at supraphysiologic exposure levels is a strong indicator of pharmacologic rather than biological failure

How GLP-1 Drives Weight Loss

10.1152/ajpendo.00373.2007

A recent systematic review and meta-analysis encompassing 76 RCTs demonstrated that GLP-1 RA therapy considerably elevated the probability of gallbladder and biliary disorders (pooled relative risk, 1.37