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13 Although preclinical and early clinical utilisation data suggested that medullary thyroid cancer and pancreatitis are increased by use of GLP-1 analogues, more extensive evaluation including through the many large-scale CVD outcome trials has not confirmed these associations

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But it tends not to last, and it's unlikely to be the driver of meaningful, sustained weight loss

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(20) Semaglutide is found under various brand names and forms

Lower ESRD prevalence in the GLP-1RA arm could similarly contribute modest positive confounding