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Kidney Impairment Noveltreat should be used with caution in the case of kidney impairment, particularly in those with severe renal disease

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10.1006/exnr.1993.1095 [DOI] [PubMed] [Google Scholar] 194.Langlet F, Mullier A, Bouret SG, Prevot V, Dehouck B

Clinical trials show that patients who escalate doses gradually experience fewer nausea episodes and better long-term adherence than those who jump to higher doses quickly

U., Friesen, J

Diarrhoea: usually mild and short-lived
