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Diarrhea is severe enough to cause dehydration

If you are transitioning from a 1 mg/mL vial to a 2 mg/mL vial, you need to draw exactly half the volume to get the same dose

Metabolic dysfunction-associated steatotic liver disease (MASLD): the interplay of gut microbiome, insulin resistance, and diabetes

Methods We searched PubMed, Embase, Cochrane and ClinicalTrials.gov up until 27 October 2021 for randomised controlled trials with a duration of at least 12 weeks that compared once-weekly tirzepatide 5, 10 or 15 mg with placebo or other glucose-lowering drugs in adults with type 2 diabetes irrespective of their background glucose-lowering treatment

116 demonstrated that the use of dual therapy of metformin, whether with GLP-1RAs or TZDs, was superior to monotherapy in improving hyperandrogenemia in women with PCOS

Routine monitoring of renal function and electrolytes is essential in this population