glp 1 weight loss mechanism of action GLP-1 Therapy Part 1: Setting Realistic Expectations – Sarah Hormachea Current Insights, Advantages and Challenges

In recent years, the pharmaceutical landscape has seen the emergence of glucagon-like peptide-1 (GLP-1) receptor agonists (RAs) such as semaglutide and tirzepatide, offering promising outcomes in weight reduction for those struggling with obesity

Closing Thought For telehealth founders and CEOs, the message is clear: Prescribing GLP-1 medications is table stakes

Last reviewed: June 18, 2026 Last updated: June 18, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

At worst, you waste money and experience unintended side effects

At least one alkaline Lys residue is contained in the C-terminals of GLP-1, exenatide, and GIP

The cagrilintide side effect profile and the cagrilintide weight loss data suggest this amylin analog could offer a complementary or alternative approach to GLP-1 therapy