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Low-grade inflammation (median hsCRP approximately 4.1 g/mL) and immune activation markers were common, underscoring the clinical relevance of slowing biological aging in this setting

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A combined genetic score showed up to a 30% difference in HbA1c reduction be-tween low- and high-response carriers, highlighting the clinical relevance of these variants, though effects were specific to GLP-1 receptor agonists and not other drug classes

GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces in response to food
