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These agents target multiple hormone pathways involved in appetite regulation, insulin secretion, energy expenditure, and hepatic metabolism

Future research should prioritize human trials, bioavailability optimization, and synergistic formulations to harness the full therapeutic potential of plant-derived GLP-1 agonists in metabolic disorders.
Two of the most popular bariatric procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), are commonly considered metabolic surgeries because they are thought to affect metabolism in a weight lossindependent manner

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