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To investigate whether the truncated QMP/LX would be recycled as well as the full-length QMP in vivo, we performed a half-life study in transgenic Tg32 mice expressing human FcRn (human FcRn Tg32) (Fig

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On the other hand, GLP-1R signaling in astrocytes was proven to be essential for maintaining mitochondrial integrity and function of the hypothalamic astrocytes, as deletion of GLP-1Rs resulted in the adaptive cellular stress response with the improvement of glucose metabolism and memory formation [97]

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