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It's a peptide that mimics a hormone called glucagon-like peptide-1 (GLP-1), so they're called GLP-1 RAs, or receptor agonists (an agonist is something that produces a physiological response), and are administered by an injection

Blood pressure changes create another layer of complexity

Third, pH shifts occur during freezing because buffer components freeze out of solution at different rates, temporarily creating pockets of extreme pH

Given the difference between the relatively short duration of clinical trials for this drug and the longer periods of use recommended by many doctors, individuals taking tirzepatide should work with their prescribers to weigh the risks and benefits involved in the continued use of this medication

However, for many, the potential of semaglutide represented a stepping stone to the future, with dual incretin therapies, namely tirzepatide, gaining momentum in clinical trial programs

Never discontinue tirzepatide without medical guidance , as abrupt cessation in patients with diabetes can lead to significant hyperglycemia