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As use of these drugs continues to expand, it becomes increasingly important to understand their real-world benefits and risks across populations. Guo conducted this research in collaboration with William Donahoo, M.D., clinical professor and chief of the UF Health Division of Endocrinology, Diabetes and Metabolism, and Steven T DeKosky, M.D., deputy director of the McKnight Brain Institute and professor of Alzheimer's research, neurology and neuroscience in the UF Department of Neurology

The comparison between semaglutide, tirzepatide, and retatrutide reveals the rapidly advancing science of GLP-1 based treatments

It is recommended with both weight loss drugs to maintain a healthy diet and regular exercise routine

Tirzepatide activates both GIP and GLP-1 receptors, which may alter tolerability and gastrointestinal effects compared to semaglutide's single GLP-1 mechanism

The mechanism of action involves mimicking the naturally occurring hormone GLP-1, which is released from the intestine after eating

Pendulum Therapeutics GLP-1 Probiotic ($65) is available for purchase starting March 13, 2024 on PendulumLife.com and Amazon